
Once upon a time, in a faraway land, Watase Yuu became envious of Chobits, Video Girl Ai, Saber Marionette, and the rest of the loser-guy-gets-a-sexbot genre, and decided that she would make her own loser-girl-gets-a-sexbot series. It was exactly like all the others, except by Watase Yuu. The end.
Accel World, by Kawahara Reki, Aigamo Hiroyuki, and probably the Devil
In the future, everyone has an internet port installed in their necks at a young age, which allows you to enter a Second Life-like virtual reality. An insecure fat kid named Haruyuki plays virtual reality games to escape from daily bullying. His skill at gaming attracts the attention of the most popular girl in school, who invites him to join a secret game called Brain Burst, which confers special real-world powers on its players.

I hope that this manga represents the industry's apex of cynical calculation, because the thought of what lies beyond this peak cannot but terrify. It was, obviously, released in conjunction with a light novel series, an anime, a video game, and at least two other separate manga, in a hideous supernova of corporate evil.
Vampire Knight, by Hino Matsuri

Yuuki is a human girl who is simultaneously in love both with Zero, a short-tempered tsundere human boy, and Kaname, the gentle but ambiguously ominous vampire boy who once saved her life. It takes only a bare modicum of genre knowledge to realize that any relationship she might form with the Kaname is horribly doomed - especially once Zero turns into a vampire himself to up his exoticism and danger to appropriate levels. Unusually, this does not stop Hino Matsuri from taking Yuuki as far as possible along the wrong track without actually showing her having sex with Kaname. (It runs in Hana to Yume, which I don't think lets you do that.)
This is enjoyable angst-ridden shoujo with 200% the FDA's daily recommended intake of unresolved sexual tension. Unlike those other two manga I just discussed, however, it's not as slick a formula thing as Hana to Yume would probably like it to be. Hino cuts off plotlines at odd times, suffers from a problematic inability to make her male characters visually distinct from one another, and forgets to establish characters who will be important until the chapter in which they became important. (At one point I think she actually does this in the notes-from-the-author sidebar.)
This won't bother you if you're skimming over the other stuff to get to the scenes between Yuuki, Kaname, and Zero which is probably the sanest thing to do. While their relationships make perfect emotional sense, if introduced to even the slightest whiff of logic this series would disintegrate.